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 Asperger's
       Introduction
       Treatment
       Prognosis
       Research
       References
       Organizations

Asperger's

Introduction What is Asperger Syndrome?
Asperger syndrome (AS) is a pervasive developmental disorder characterized by an inability to understand how to interact socially. Other features include clumsy and uncoordinated motor movements, social impairment with extreme obtuseness, limited interests and/or unusual preoccupations, repetitive routines or rituals, speech and language peculiarities, and non-verbal communication problems. Generally, children with AS have few facial expressions apart from anger or misery. Most have excellent rote memory and musical ability, and become intensely interested in one or two subjects (sometimes to the exclusion of other topics). They may talk at length about a favorite subject or repeat a word or phrase many times. Children with AS tend to be "in their own world" and preoccupied with their own agenda. AS is commonly recognized after the age of 3. Some individuals who exhibit features of autism (a developmental brain disorder characterized by impaired social interaction and communication skills) but who have well-developed language skills may be diagnosed with AS, although high-functioning autism differs from AS in early language delay.

Is there any treatment?
There is no specific course of treatment or cure for AS. Treatment, which is symptomatic and rehabilitational, may include both psychosocial and psychopharmacological interventions such as psychotherapy, parent education and training, behavioral modification, social skills training, educational interventions, and/or medications including psychostimulants, mood stabilizers, beta blockers, neuroleptics, and tricyclic antidepressants.

What is the prognosis?
Children with AS have a better outlook than those with other forms of pervasive developmental disorders, and are much more likely to grow up to be independently functioning adults. Nonetheless, in most cases, these individuals will continue to demonstrate, to some extent, subtle disturbances in social interactions. There is also an increased risk for development of psychosis (a mental disorder) and/or mood problems such as depression and anxiety in the later years.

What research is being done?
The NINDS conducts and supports a broad range of research on developmental disorders including AS. The goals of these studies are to increase understanding of these disorders and to find ways to treat, prevent, and ultimately cure them.

Selected references
Bishop, D. Autism, Asperger's Syndrome and Semantic-Pragmatic Disorder: Where Are the Boundaries? British
. Journal of Disorders of Communication, 24; 107-121 (1989)

Gillberg, C. Asperger Syndrome in 23 Swedish Children Developmental Medicine and Child Neurology, 31; 520-531 (1989)

Gillberg, C. Outcome in Autism and Autistic-like Conditions Journal of the American Academy of Child and Adolescent Psychiatry, 30:3; 375-382 (May 1991)

Szatmari, P.  Asperger's Syndrome: Diagnosis, Treatment, and Outcome Psychiatric Clinics of North America, 14:1; 81-93 (1991)

Kerbeshian, J, et al. Asperger's Syndrome: To Be or Not To Be? British Journal of Psychiatry, 156; 721-725 (1990) 

Organizations
Asperger Syndrome Education Network
P.O. Box 2577 
Jacksonville FL 32203-2577 
aspen@cybermax.net 
Tel: 609-890-2404 

Learning Disabilities Association of America
4156 Library Road 
Pittsburgh PA 15234-1349 
Tel: 412-341-1515 412-341-8077 
Fax: 412-344-0224 

National Organization for Rare Disorders (NORD)
P.O. Box 8923 
(100 Route 37) 
New Fairfield CT 06812-8923 
orphan@rarediseases.org 
www.rarediseases.org
Tel: 203-746-6518 800-999-NORD (-6673) 
Fax: 203-746-6481 

NICHD/National Institute of Child Health and Human Development, NIH 
Bldg. 31, Rm. 2A32 
Bethesda MD 20892-2425
NICHDdClearinghouse@mail.nih.gov 
www.nichd.nih.gov
Tel: 301-496-5133 

NIMH/National Institute of Mental Health, NIH 
6001 Executive Blvd. Room 8184, MSC 9663 
Bethesda MD 20892-9663 
nimhinfo@nih.gov 
www.nimh.nih.gov/
Tel: 301-443-4513 Depression Info: 800-421-4211 

This information is available courtesy of the National Institute of Neurological Disorders and Stroke.  It is in the public domain and can be downloaded, reproduced, or copied without permission. For more information go to 
http://www.ninds.nih.gov/health_and_medical/disorder_index.htm

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