Clinical  Research  Center

Publications

MHCRC Publications

1984-1999

1.      Ahearn EP, Steffens DC, Cassidy F, Van Meter SA, Provenzale JM, Seldin MF, Weisler RH, Krishnan KR. Familial leukoencephalopathy in bipolar disorder.  Am J Psychiatry 155(11):1605-1607, November 1998.

2.      Bissette G,  Seidler FJ,  Nemeroff CB, and Slotkin TA. High affinity choline transporter status in alzheimers disease tissue from rapid autopsy.  Annals of the New York Academy of Sciences 777:197-204, 1996.

3.      Blakely RD, Berson HE,  Fremeau Jr RT,  Caron  MG,  Peek MM, Prince HK,  Bradley CC. Cloning and expression of a functional serotonin transporter from rat brain.  Nature 354:66-70, 1991.

4.      Blazer D.  Clinical features in depression in old age:  a case of minor depression.   Current Opinion in Psychiatry 4:596-599, 1991.

5.      Blazer D. Depression in late life.  Current Opinion in Psychiatry 2:515-519, 1989.

6.      Blazer D.  Depression in the elderly.   New England Journal of Medicine 320:14-166, 1989.

7.      Blazer  D. General principles in aging.  In: Geriatrics Review Syllabus:  A Core Curriculum in Geriatric Medicine; Book I, Syllabus and Questions, JC Beck, (ed.), American Geriatrics Society, New York, New York, 1989-90 Program. 

  8.      Blazer D, Bachar JR, Hughes DC. Major depression with melancholia: a comparison of middle-aged and elderly adults.  Journal of the American Geriatrics Society. 35(10):927-32, 1987.

  9.      Blazer D, Hughes DC. Subjective social support and depressive symptoms in major depression: separate phenomena or epiphenomena. Journal of Psychiatric Research,  25(4):191-203, 1991.

10.  Blazer D,  Hughes DC, Fowler N.  Anxiety as an outcome symptom of depression in elderly and middle-aged adults.   Intl Journal of Geriatric Psychiatry 4:273-278, 1989.

  11.  Blazer D, Hughes DC,  George LK. Age and impaired subjective support:  predictors of depressive symptoms at one-year follow-up.  The Journal of Nervous and Mental Disease 180(3):172-178, 1992.

  12.  Blazer D, Swartz, M,  Woodbury M,  Manton KG,  Hughes D, George LK.  Depressive symptoms and depressive diagnoses in a community population.  Arch Gen Psychiatry 45:1078-1084, 1988.

  13.  Blazer D, Woodbury M, Hughes DC, George LK, Manton KG, Bachar JR,  Fowler N. A statistical analysis of the classification of depression in a mixed community and clinical sample.  Journal of Affective Disorders 16:11-20, 1989.

14.  Broadhead WE, Tse C-KJ, Burns BJ, Sigmon A, Yarnall KSH,  Walker R. Three month follow-up of minor depression in family practice.  Seventh Annual NIMH International Research Conference on Mental Health Problems in the General Health Sector, 1993.

15.  Broadhead WE, Weissman MM, Barrett JE, Blacklow RS, Gilbert TT,  Keller MB, Higgins, E.  The SDDS-PC^TM screening questionnaire for multiple mental disorders in primary care:  A validation study.  Seventh Annual NIMH International Research Conference on Mental Health Problems in the General Health Sector, 1993.

16.  Brummett BH, Barefoot JC, Siegler IC, Steffens DC.  The relation of subjective and received social support to clinical and self-report assessments of depression in an elderly population.  J. Consulting Clinical Psychology (in press). 

 17.  Carroll BJ. Brain mechanisms in manic depression. Clinical Chemistry 40(2):303-8, 1994

18.  Carroll  BJ.  Diagnostic validity and laboratory studies.  Rules of the game.  In: The Validity of Psychiatry Diagnosis, Robins LN, Barrett JE, (eds.), Raven Press, New York, 229-245, 1989.

19.  Carroll BJ.  Psychopathology and neurobiology of manic-depressive disorders.  In: Psychopathology and the Brain.  BJ Carroll and JE Barrett (eds.), Raven Press, New York, 265-285, 1991.

 20.  Charles HC, Lazeyras F, Krishnan KRR, Boyko OB, Patterson LJ, Doraiswamy PM, McDonald WM.  Proton spectroscopy of human brain: effects of age and sex.  Prog Neuro-psychopharmacol. & Biol Psychia 18(6):995-1004, 1994.

21.  Charles HC, Lazeyras F, Krishnan KRR, Boyko OB, Payne M, Moore D.  Brain choline in depression: In vivo detection of potential pharmacodynamic effects of antidepressant therapy using hydrogen localized spectroscopy.  Prog. Neuro-Psychopharmacol & Biol Psy 18(7), 1994.

22.  Clark LM, McDonald WM, Welsh-Bohmer KA, Siegler IC, Dawson DV, Tupler LA, Krishnan KR.  Magnetic resonance imaging correlates of depression in early- and late-onset alzheimer's disease.   Biol Psychiatry 1998 Oct 1:44(7):592-599.   

23.  Coffey CE,  Wilkinson WE,  Weiner RD,  Parashos JA,  Djang WT,  Webb MC,  Figiel GS,  Spritzer CE. Quantitative cerebral anatomy in depression: a controlled magnetic resonance imaging study.  Arch Gen Psychiatry, 50:7-16, 1993.

 24.  Craighead WE and Craighead LW.  Behavior therapy: recent developments.  Current Opinion in Psychiatry 3:785-789, 1990.

 25.  Craighead WE and Evans DD.  Factor analysis of the Montgromery-Asberg depression rating scale.  Depression 4:31-33, 1996.

26.  Craighead WE, Evans DD, Robins, CJ. Unipolar depression. In: SM Turner, KS Calhoun, HE Adams (eds.), Handbook of Clinical Behavior Therapy (2nd ed., pp. 99-116), New York:  John Wiley & Sons, 1992.

 27.  Davidson JRT,  Boyko OB, Charles HC, Krishnan KRR, Potts N, Ford SM, Patterson LA. MRS in social phobia: preliminary findings.  J Clin Psychiatry 54(12):19-25, 1993.

 28.  Dearry A, Gingrich JA,  Falardeau P,  Fremeau Jr RT, Bates MD,  Caron MG.  Molecular cloning and expression of the gene for a human D₁ dopamine receptor.  Nature, 347(6288), 72-76, 1990.

29.  Doraiswamy PM,  Tupler LA, Krishnan KR.  Neuroleptic treatment and caudate plasticity.  The Lancet 345(8951):734-735, March 1995.

30.  Doraiswamy PM, Patterson L, Na C, Husain MM, Boyko O, McDonald WM, Krishnan KRR. Bicaudate index on magnetic resonance imaging: effects of normal aging.  J  Geriatric Psychiatry and Neurology 7(1):13-17, 1994.

31.  Escalona PR,  Early B, McDonald WM, Doraiswamy PM,  Shah SA,  Husain MM,  Boyko OB,  Figiel GS,  Ellinwood EH,  Nemeroff CB, Krishnan KRR.  Reduction of cerebellar volume in major depression: a controlled MRI study.  Depression 1:156-158, 1993.

32.  Figiel GS, Coffey CE, Weiner, RD.  Brain magnetic resonance imaging in elderly depressed patients receiving electroconvulsive therapy.  Convulsive Therapy 5(1):26-34, 1989.

33.  Flint DP, Hays JC, Krishnan, KRR, Meador KG, Blazer, DG.  Suicidal behaviors in depressed men with a family history of suicide:  effects of psychosocial factors and age.  Aging and Mental Health 2:286-299, 1998.

34.  Fumagalli  F, Jones SR,  Caron MG,  Seidler FJ, Slotkin TA. Expression of mRNA coding for the serotonin transporter in aged vs. young rat brain: differential effects of glucocorticoids.  Brain Research 719:225-228, 1996.

35.  George LK.  Social and economic factors related to psychiatric disorders in late life.  In: Geriatric Psychiatry, Chapter 8, Busse EW and Blazer DG, eds.  Washington, DC, American Psychiatric Press, 1989. 

36.  George LK.  Social factors and depression in late life.  In: Schneider LS, Reynolds CF,  Lebowitz B, Friedhoff A., eds.  Diagnosis and Treatment of Depression in the Elderly:  Proceedings of the NIH Consensus Development Conference, Chapter 9, Washington DC:  American Psychiatric Press, in press.

37.  George LK.  Social factors and the onset and outcome of depression.  In: Schaie KW, Hause JS, Blazer, DG, eds.  Aging, Health Behaviors, and Health Outcomes.  Hillsdale NJ:  Lawrence Erlbaum Associates, 137-159, 1992.

38.  George LK, Blazer DG, Hughes DC, Fowler N.  Social support and the outcome of major depression.  British Journal of Psychiatry 154:478-485, 1989.

39.  Gingrich JA, Andersen PH,  Tiberi M,  El-Mestikawy S, Jorgensen PN, Fremeau Jr RT,  Caron MG.  Identification, characterization, and molecular cloning of a novel transporter-like protein localized to the central nervous system.  FEBS 312(2,3) 115-122, 1992.

40.  Giros B,  El-Mestikawy  S,  Bertrand L,  Caron MG.  Cloning and functional characterization of a cocaine-sensitive dopamine transporter.  FEBS 295(1,2,3):149-154, 1991.

41.  Giros B, and Caron MG.   Molecular characterization of the dopamine transporter.  Trends in Pharmacological Sciences 14(2):43-49, 1993.

42.  Giros B, El-Mestikawy S, Godinot N, Zheng K, Han H, Yang-Feng T, Caron, MG. Cloning, pharmacological characterization, and chromosome assignment of the human dopamine transporter.  Molecular Pharmacology 42:383-390, 1992.

43.  Gonzalez MB, Snyderman TB, Colker JT,  Arias, RM, Jian JW, O’Connor CM, and Krishnan R. Depression in patients with coronary artery disease.  Depression 4:57-62, 1996.

44.  Greenwald BS, Kramer-Ginsberg E, Krishnan , KRR,  Ashtari M,  Aupperle PM,  and Patel M. MRI signal hyperintensities in geriatric depression.  American Journal of Psychiatry 153:9, September 1996.

45.  Greenwald BS, Kramer-Ginsberg E, Krishnan KRR, Ashtari M, Aupperle PM, Patel M. Magnetic resonance imaging signal hyperintensities in geriatric depression.  American J Psychiatry 153:1212-1215, 1996.

46.  Greenwald BS, Kramer-Ginsberg E, Krishnan KRR, Ashtari M, Aupperle PM, and Patel M. MRI signal hyperintensities in geriatric depression.  Am J Psychiatry 153:9, 1996.

47.  Hays  JC, Krishnan KRR, George LK, Pieper, CF, Flint EP, Blazer DG. Psychosocial and physical correlates of chronic depression.  Psychiatry Research 72:149-159, 1997.

48.  Hays JC, Krishnan KRR, George LK, Blazer DG.  Age of first onset of bipolar disorder: demographic, family history and psychosocial correlates.  Depression and Anxiety 7:76-82, 1998.

49.  Hays JC, Landerman RL, George LK, Flint EP, Koenig H, Blazer DG.  Social correlates of the dimensions of depression in the elderly.  Journals of Gerontology: Psychological Sciences 53B:31-39, 1998.

50.  Hays JC, Saunders WB, Flint EP, Kaplan BH, Blazer DG.  Social support and depression as risk factors for loss of physical function in late life.  Aging and Mental Health 1:209-220, 1997.

51.  Hughes DC,  DeMallie D, Blazer DG.  Does age make a difference in the effects of physical health and social support on the outcome of a major depressive episode?  Am. J. Psychiatry 150:728-733, 1993.

52.  Keshavan MS, Anderson S, Beckwith C, Nash K, Pettegrew JW, Krishnan KR. A comparison of stereology and segmentation techniques for volumetric measurements of lateral ventricles in magnetic resonance imaging.  Psychiatry Research 61(1):53-60, 1995.

53.  Koenig HG, Cohen HJ, Blazer DG, Krishnan KRR, Sibert TE.   Profile of depressive symptoms in younger and older medical inpatients with major depression.  J Am Geriatrics Society 41(11):1169-1176, 1993.

54.  Koenig HG, Meador KG, Cohen HJ, Blazer DG. Screening for depression in hospitalized elderly medical patients:  taking a closer look.  J. Amer. Ger. Soc. 40(10):1013-1017, 1992.

55.  Krishnan  KRR. Depression-neuroanatomical substrates.  Behavior Therapy 23:571-583, 1992.

56.  Krishnan KR, George LK, Pieper CF, Jiang W, Arias R, Look A, O'Connor C.  Depression and social support in elderly patients with cardiac disease.  American Heart Journal 136(3):491-495, September 1998.

57.  Krishnan KR, Hays JC, George LK, Blazer DG.  Six-month outcomes for MRI-related vascular depression.  Depress Anxiety  8(4):142-146, 1998.

58.  Krishnan KR, Tupler LA, McDonald WM.  Background factors and clinical symptoms of major depression with silent cerebral infarction.  Stroke 25(12):2507, 1994.

59.  Krishnan KRR,  Hays JC, Blazer DG.   MRI-defined vascular depression.  American Journal of Psychiatry 154(4):497-501, April 1997.

60.  Krishnan KRR,  Ritchie JC, Saunders W,  Wilson W,  Nemeroff CB, and Carroll BJ. Nocturnal and early morning secretion of ACTH and cortisol in humans.  Biological Psychiatry 28:47-57, 1990.

61.  Krishnan KRR, McDonald WM,  Escalona PR,  Doraiswamy PM,  Na C,  Husain MM, Figiel GS,  Boyko OB, Ellinwood EH,  Nemeroff CB.  Magnetic resonance imaging of the caudate nuclei in depression.  Arch Gen Psychiatry 49:553-557, 1992.

62.  Krishnan KRR, McDonald WM, Tupler LA, Boyko OB.  Neuroanatomical substrates of depression in the elderly.  Eur Arch Psychiatry and Clinical Neuroscience 243:41-46, 1993.

63.  Krishnan KRR, McDonald WM.  Arteriosclerotic depression.  Medical Hypotheses 44(2):77-145, 1995.

64.  Krishnan KRR, Miller MN, Helms MJ, Reed D,  Ritchie JC,  Nemeroff CB,  Carroll BJ. Dose response relationship between plasma ACTH and cortisol after the infusion of ACTH_1-24.  Eur. Arch Psychiatry Clin. Neurosci. 242:240-243, 1993.

65.  Krishnan KRR, Tupler LA, Ritchie, Jr. JC, McDonald WM, Knight DL, Nemeroff CB, Carroll BJ.  ApoE-e4 frequency in geriatric depression.  Biol. Psy 40:69-71, 1996.

66.  Krishnan KRR.  Neuroanatomic substrates of depression in the elderly.  J. Ger. Psychiatry and Neurology 6:39-58, 1993.

67.  Krishnan KRR.  Organic bases of depression in the elderly.  Annu. Rev. Med. 42:261-66, 1991.

68.  Krishnan R, Ritchie JC, Saunders WB, Nemeroff CB, Carroll BJ. Adrenocortical sensitivity to low-dose ACTH administration in depression patients.  Biological Psychiatry 27:930-933, 1990.

69.  Krishnan, KRR, Hays, JC, Tupler, LA, George, LK, and Blazer, DG.  Clinical and phenomenological comparisons of late-onset and early-onset depression.  Am J Psychiatry 152(5):785-788, 1995.

70.  Lynch T, Johnson C, Mendelson T, Robin C, Krishnan R and Blazer D.  Correlates of suicide among an elderly depressed sample.  Journal of Affective Disorders, 1998, (in press).

71.  Lynch T, Johnson C, Mendelson T, Robin C, Krishnan R and Blazer D.  New onset and remission of suicidal ideation.  Journal of Affective Disorders, 1998, (in press).

72.  Lynch T, Johnson C, Mendelson T, Robin C, Krishnan R and Blazer D.  Perceived social support among depressed elderly, middle-aged and young adult samples.  Journal of Affective Disorders, 1998, (in press).

73.  MacFall JR, Byrum C, Parashos I, Charles HC, Boyko OB, Chittilla V, Krishnan KRR.  Relative accuracy and reproductibility of regional MRI brain volumes for point-counting methods.  Psychiatry Research 55:167-177, 1994.

74.  McDonald WM, Krishnan KRR, Doraiswamy PM,  Blazer DG.  Occurrence of subcortical hyperintensities in elderly subjects with mania.  Psychiatry Research:  Neuroimaging 40:211-20, 1991.

75.  Miner CM, Davidson JRT, Potts NLS, Tupler LA, Charles HC, Krishnan KRR.  Brain fluoxetine measurements using Magnetic Resonance Spectroscopy in patients with social phobia.  Biol Psychiatry 38:696-698, 1995.

76.  Nemeroff  CB,  Knight DL,  Franks J, Craighead WE, and Krishnan KRK.   Further studies on platelet serotonin transporter binding in depression.  Am J. Psychiatry 151:(11), 1623-1625, November 1994.

77.  Nemeroff CB, Knight DL, Krishnan KRR,  Slotkin TA,  Bissette G, Melville ML, Blazer DG.  Marked reduction in the number of platelet-tritiated imipramine binding sites in geriatric depression.  Arch Gen Psychiatry 45:919-923, 1988.

78.  Parashos IA, Oxley SL, Boyko OB, Krishnan KRR. In vivo quantitation of basal ganglia and thalamic degenerative changes in two temporal lobectomy patients with affective disorder.  J Neuropsychiatry and Clinical Neurosci 5(3):337-341, 1993.

79.  Parashos IA, Tupler LA, Blitchington T, Krishnan KR.   Magnetic-resonance morphometry in patients with major depression.  Psychiatry Res  9:84(1):7-15, 1998

80.  Rajagopalan P, Krishnan KR, Passe TJ, MacFall JR.   Magentic resonance using deoxyhemoglobin contrast versus positron emission tomography in the assessment of brain function.   Prog Neuropsychopharmacol Biol Psychiatry 19(3):351-366, 1995.

81.  Rajagopalan P, Passe TJ, Doraiswamy PM, Figiel GS, MacFall JR, and Krishnan, KRR. Changes in pituitary gland signal intensity and morphology as evaluated by magnetic resonance imaging in aging, depression, and by gender.  Depression 2:303-307, 1994-95.

82.  Rao VP, Krishnan KRR, Goli V, Saunders WB,  Ellinwood Jr EH,  Blazer DG,  and Nemeroff CB.  Neuroanatomical changes and hypothalamo-pituitary-adrenal axis abnormalities.  Biol Psychiatry 26:729-732, 1989.

83.  Renick SE, Seidler FJ, McCook EC, and Slotkin TA. Neuronal control of cardiac and hepatic macromolecule synthesis in the neonatal rat:  effects of sympathectomy.  Pediatric Research 41:359-363, 1997.

84.  Ritchie JC,  Owens MJ, Mayer H, Watson JT,  Kilts C, Carroll BJ.  Preliminary studies of 6b-hydroxydexamethasone and its importance in the DST.  Biological Psychiatry 32:825-833, 1992.

85.  Ritchie JC, Belkin BM, Krishnan KRR, Nemeroff CB, Carroll BJ.  Plasma dexamethasone concentrations and the dexamethasone suppression test.  Biological Psychiatry 27:159-173, 1990.

86.  Roy TS, Andrews JE, Seidler FJ, Slotkin TA.  Chlorpyrifos elicits mitotic abnormalities and apoptosis in neuroepithelium of cultured rat embryos.  Teratology 58(2):62-68, 1998.

87.  Roy TS, Andrews JE, Seidler FJ, Slotkin TA. Nicotine evokes cell death in embryonic rat brain during neurulation.  J Pharmacol Exp Ther 1998 Dec;287(3):1136-1144.

88.  Shedlack KJ, Eun-Kyu L, Radtke RA, Friedman AH, Crain JB, Boyko OB, Krishnan KRR. Ipsilateral subcortical atropy associated with temporal lobectomy.  Psychiatry Research: Neuroimaging 54:295-304,1994.

89.  Shedlack KJ, McDonald WM, Laskowitz, DT, Krishnan, KRR.  Geniculocalcarine hyperintensities on brain magnetic resonance imaging associated with visual hallucinations in the elderly.  Psychiatry Research: Neuroimaging 54:283-293, 1994.

90.  Slotkin  TA,  Hays JC, Nemeroff CB, and Carroll BJ.  Dexamethasone suppression test identifies a subset of elderly depressed patients with reduced platelet serotonin transport and resistance to imipramine inhibition of transport.   Depression and Anxiety 6:19-25, 1997.

91.  Slotkin TA,  Nemeroff CB,  Bissette G, and  Seidler FJ.  Overexpression of the high affinity choline transporter in cortical regions affected by alzheimer’s disease: evidence from rapid autopsy studies.  Journal of Clinical Investigation 94:696-702, 1994.

92.  Slotkin TA, Zhang J.  McCook EC, and  Seidler FJ.  Glucocorticoid-targeting of the adenylyl cyclase signaling pathway in the cerebellum of young versus aged rats.  Brain Research, 800:236-244, 1998.

93.  Slotkin TA,  Barnes GA, McCook EC,   Seidler FJ.   Programming of brainstem serotonin transporter development by pernatal glucocorticoids.  Developmental Brain Research 93:155-161, 1996.

94.  Slotkin TA,  Lorber BA,  McCook EC,  Barnes GA,  and  Seidler FJ.  Neural input and the development of adrenergic cell signaling:  neonatal denervation evokes neither receptor upregulation nor persistent supersensitivity of adenylate cyclase.  Developmental Brain Research 88:17-29, 1995.

95.  Slotkin TA,  McCook EC,  Seidler FJ. Glucocorticoids regulate the development of intracellular signaling: enhanced forebrain adenylate cyclase catalytic subunit activity after fetal dexamethasone exposure.  Brain Research Bulletin 32:359-362, 1993.

96.  Slotkin TA,  McCook EC, Ritchie JC, and Seidler FJ.  Do glucocorticoids contribute to the abnormalities in serotonin transporter expression and function seen in depression?  An animal model.   Biological Psychiatry 40:576-584, 1996.

97.  Slotkin TA,  Miller DB,  Fumagalli F, McCook EC,  Zhang J,  Bissette G, and Seidler FJ. Modeling geriatric depression in animals:  biochemical and behavioral effects of olfactory bulbectomy in young versus aged rats.  Journal of Pharmacology and Experimental Therapeutics 289:334-345,1999.

98.  Slotkin TA,  Saleh JL,  Zhang J, and  Seidler FJ. Ontogeny of b-adrenoceptor/adenylyl cyclase desensitization mechanisms:  the role of neonatal innervation.  Brain Research 742:317-328, 1996.

99.        Slotkin TA,  Whitmore WL,  Barnes GA, Krishnan KRR, Blazer DG,  Knight DL,  Nemeroff CB.  Reduced inhibitory effect of imipramine on radiolabeled serotonin uptake into platelets in geriatric depression.  Biol. Psychiatry, 25:687-691, 1989.

100.    Slotkin TA, Lappi SE, McCook EC,  Tayyeb MI,  Eylers JP,  Seidler FJ. Glucocorticoids and the development of neuronal function:  effects of prenatal dexamethasone exposure on central noradrenergic activity.   Biol. Neonate 61:326-336, 1992.

101.    Slotkin TA, Lappi SE, Tayyeb MI,  Seidler FJ.  Dose-dependent glucocorticoid effects on noradrenergic synaptogenesis in rat brain:  ontogeny of [³H]desmethylimipramine binding sites after fetal exposure to dexamethasone.   Research Communications in Chemical Pathology and Pharmacology 73(1):3-19, 1991.

102.    Slotkin TA, McCook EC, Nemeroff CB, Seidler, FJ. Species differences in a₂-adrenergic regulation of platelet adenylate cyclase.  Research Communications in Chemical Pathology and Pharmacology 72(3):259-271, 1991.

103.    Slotkin TA, McCook EC, Seidler FJ.  Cryptic brain cell injury caused by fetal nicotine exposure is associated with persistent elevations of c-fos protooncogene expression.  Brain Research 750:180-188, 1997.

104.    Slotkin TA, McCook EC, Ritchie JC, Carroll BJ, Seidler FJ.  Serotonin transporter expression in rat brain regions and blood platelets:  aging and clucocorticoid effects.  Biological Psychiatry  41:172-183, 1997.

105.    Slotkin TA, Seidler FJ, Ritchie JC.  Effects of aging and glucocorticoid treatment on monoamine oxidase subtypes in rat cerebral cortex: therapeutic implications.  Brain Res Bull 1:47(4):345-348, November 1998.

106.    Slotkin TA, Thai  L, McCook EC, Saleh JL, Zhang J, and Seidler FJ. Aging and glucocorticoids:  effects on cell signaling mediated through adenylyl cyclase.  The Journal of Pharmacology and Experimental Therapeutics 279(2):478-491, 1996.

107.    Slotkin TA, Zhang J, McCook EC, Seidler FJ.  Glucocorticoid administration alters nuclear transcription factors in fetal rat brain: implications for the use of antenatal steroids.  Brain Res Dev Brain Res 1:111(1):11-24, November 1998.

108.    Soares JC, Krishnan KRR, Keshavan MS. Nuclear magnetic resonance spectroscopy:  new insights into the pathophysiology of mood disorder.  Depression 4:14-30, 1996.

109.    Steffens DC, Hays JC, Krishnan KRR. Disability in geriatric depression.  Am J Geriatr Psychiatry 7:34-40, 1997.

110.    Steffens DC, O'Connor CM, Jiang WJ, Pieper CF, Kuchibhatla MN, Arias RM, Look A, Davenport C, Gonzalez MB, Krishnan KRR.  The effect of major depression on functional status in patients with coronary artery disease.  J Am Geriatr Soc 47(3):319-322, 1999.  Poster presentation at 51st Annual Meeting, Gerontological Society of America, Philadelphia, November, 1998.

111.    Steffens DS, Hays JC,  George LK,  Krishnan KRR and Blazer DG.  Sociodemographic and clinical correlates of number of previous depressive episodes in the depressed elderly.  Journal of Affective Disorders, 39:99-106, 1996.

112.    Thai L, Galluzzo JM, McCook EC, Seidler FJ, and Slotkin TA.  Atypical regulation of hepatic adenylyl cyclase and adrenergic receptors during a critical developmental period:  agonists evoke supersensitivity accompanied by failure of receptor down-regulation.  Pediatric Research 39:697-707, 1996.

113.    Thakur M and Krishnan KRR.  Delusional and non-delusional depression in the elderly – a comparative study.  Psychiatry Research, 1998, (in press).

114.    Thakur M, Hays J, Krishnan RR.  Clinical, demographic and social characteristics of psychotic depression.  Psychiatry Research 86: 99-106, 1999.

115.    Tiberi M, Jarvie KR, Silvia C, Falardeau P,  Gingrich JA, Godinot N, Bertrand L, Yang-Feng TL,  Fremeau Jr RT,  Caron, MR.  Cloning, molecular characterization, and chromosomal assignment of a gene encoding a second d₁ dopamine receptor subtype:  differential expression pattern in rat brain compared with the D_1a receptor.  Proc. Natl. Acad. Sci, USA, 88, 7491-7495, 1991.

116.    Trauth JA, Seidler FJ, McCook EC, Slotkin TA.  Persistent c-fos induction by nicotine in developing rat brain regions: interaction with hypoxia.   Pediatr Res. 45(1):38-45, 1999.

117.    Turnbull JE, George LK, Landerman R, Swartz MS, Blazer DG.  Social outcomes related to age of onset among psychiatric disorders.  J. Consult. and Clin. Psychology 58(6):832-839, 1990.

118.    Watkins LL, Kuchibhatla M, Davenport C, Krishnan KRR. Generalized anxiety disorder in coronary artery disease patients:  effects of low social support and negative life events.   J Psychosomatic Research (under review) 1999.

119.      Xanthakos S, Krishnan KRR, Kim D, Charles HC. Magnetic resonance imaging of alzheimer’s disease.  Prog Neuro-Psychopharmaol & Biol Psychiat 20:597-626, 1996.

120.    Zeiders  JL,  Seidler FJ,  and Slotkin TA. Ontogeny of regulatory mechanisms for b-adrenoceptor control of rat cardiac adenylyl cyclase:  targeting of G-proteins and the cyclase catalytic subunit.  Journal of Molecular and Cellular Cardiology 29:603-615, 1997.

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Karen L. Taylor

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