120. MacFall JR, Taylor WD, Rex, Pieper C, Payne ME, McQuoid DR, Steffens DC, Krishnan KR.  Lobar Distribution of lesion volumes in late-life depression: The Biomedical Informatics Resource Network (BIRN).  Neuropsychopharmacology 2006;31(7):1500-7.
PubMed Abstract

119.  Taylor WD, Steffens DC, Krishnan KR.  Psychiatric disease in the twenty-first century: the case for subcortical ischemic depression.  Biol Psychiatry. 2006;60:1299-1303.
PubMed Abstract

118.  Sair HI, Welsh-Bohmer KA, Wagner HR, Steffens DC.  Ascending digits task as a measure of executive function in geriatric depression.  J Neuropsychiatry Clin Neurosci. 2006 Winter;18(1):117-20.
PubMed Abstract

117.  Hannestad J, Taylor WD, McQuoid DR, Payne ME, Krishnan KR, Steffens DC, Macfall JR.  White matter lesion volumes and caudate volumes in late-life depression.  Int J Geriatr Psychiatry. 2006;21(12):1193-8
PubMed Abstract

116.  Greenberg DL, Payne ME, Macfall JR, Provenzale JM, Steffens DC, Krishnan RR.  Differences in brain volumes among males and female hormone-therapy users and nonusers.  Psychiatry Res. 2006 Oct 30;147(2-3):127-34.
PubMed Abstract

115.  Bae JN, Macfall JR, Krishnan KR, Payne ME, Steffens DC, Taylor WD.  Dorsolateral Prefrontal Cortex and Anterior Cingulate Cortex White Matter Alterations in Late-Life Depression.  Biol Psychiatry 2006;60(12):1356-63.
PubMed Abstract

114.  Hybels CF, Blazer DG, Steffens DC.  Partial remission. A common outcome in older adults treated for major depression.  Geriatrics. 2006 Apr;61(4):22-6.
PubMed Abstract

113.  Payne ME, Hybels CF, Bales CW, Steffens DC. Vascular nutritional correlates of late-life depression.Am J Geriatr Psychiatry. 2006 Sep;14(9):787-95
PubMed Abstract

112.  Chen P-S, McQuoid DR, Payne ME, Steffens DC.  White matter and subcortical gray matter lesion volume changes and late-life depression outcome: a four-year magnetic resonance imaging study.  Int Psychogeriatrics 2006;18(3):445-56
PubMed Abstract

111.  Lekwauwa RE, McQuoid DR, Steffens DC.  Hippocampal volume is associated with physician-reported acute cognitive deficits post-ECT.  J Geriatric Psychiatry Neurology 2006;19:21-25.
PubMed Abstract

110.  Stephen Tyring, Alice Gottlieb, Kim Papp, Ken Gordon, Craig Leonardi, Andrea Wang, Deepa Lalla, Michael Woolley, Angelika Jahreis, Ralph Zitnik, David Cella, Ranga Krishnan:  Etanercept and clinical outcomes, fatigue, and depression in psoriasis: double-blind placebo-controlled randomised phase III trial.  Lancet. 2006 Jan 7;367(9504):29-35.
PubMed Abstract

109. Jeste ND, Hays JC, Steffens DC: Clinical correlates of anxious depression among elderly patients. J Affect Disord 2006;90:37-41.
PubMed Abstract

Publications, 2005:

108. Lekwauwa RE, McQuoid DR, Steffens: Hippocampal volume as a predictor of short-term ECT outcomes in older patients with depression. Am J Geriatr Psychiatry. 2005 Oct;13(10):910-3. 
PubMed Abstract

107. Hybels CF, Steffens DC, McQuoid DR, Krishnan KR: Residual symptoms in older patients treated for major depression. Int J Geriatr Psychiatry. 2005 Dec;20(12):1196-202.

PubMed Abstract

106. Pogorelov VM, Rodriguiz RM, Insco ML, Caron MG, Wetsel WC: Novelty seeking and stereotypic activation of behavior in mice with disruption of the Dat I gene.  Neuropsychopharmacology 30, 1818-1831, 2005. (Corrigendum: 1772)  

 PubMed Abstract

105. Sotnikova TD, Beaulieu JM, Barak LS, Wetsel WC, Caron MG, Gainetdinov RR: Dopamine-independent locomotor actions of amphetamines in a novel acute model of Parkinson’s disease. PloS Biology 3: 1488-1500, 2005.

 PubMed Abstract

104. Jacobsen JPR, Rodriguiz RM, Mørk A, Wetsel WC: Monoamine dysregulation in glutathione-deficient mice: possible relevance to schizophrenia?  Neurosci 132: 1055-1072, 2005.

 PubMed Abstract

103. Beaulieu JM, Sotnikova TD, Marion S, Lefkowitz RJ, Gainetdinov RR, Caron MG: A b arrestin 2 signaling complex mediates dopaminergic neurotranmission and behavior.  Cell 122: 261-273, 2005.

PubMed Abstract

102. Cyr M, Caron MG, Johnson GA , Laakso A: Magnetic resonance imaging at microscopic resolution reveals subtle morphological changes in a mouse model of dopaminergic hyperfunction.  NeuroImage 26: 83-90, 2005.

PubMed Abstract

101. Pillai-Nair N, Panicker AK, Rodriguiz RM, Miller K, Demyanenko GP, Huang J, Wetsel WC, Maness PF: NCAM-Secreting transgenic mice display abnormalities in GABAergic interneurons and alterations in behavior.  J Neurosci 25: 4659-4671.
PubMed Abstract

            100. Torres GE, Caron MG: Approaches to identify monoamine transporter interacting proteins.   J. Neurosci. Methods 143: 63-68, 2005.
PubMed Abstract

            99. Kim KM, Gainetdinov RR, Laporte SA, Caron MG, Barak LS: G protein-coupled receptor kinase regulates dopamine D3 receptor signaling by modulating the stability of a receptor-filamin-beta-arrestin complex.  A case of autoreceptor regulation.  J Biol Chem 280: 12774-12780, 2005.
PubMed Abstract

98. Rajkowska G, Dubey P, Miguel-Hidalgo JJ, Stockmeier CA and Krishnan RR: Prominent reduction in pyramidal neurons density in orbitofrontal cortex in elderly depressed patients. Biol Psychiatry 58: 297-306, 2005.
PubMed Abstract

97. Wang L, Song AW, McCarthy G, LaBar K: Amydala activation to sad pictures during high-field (4 Tesla) functional MRI.  Emotion 5: 12-22, 2005.
 PubMed Abstract

96.   Voils CI, Steffens DC , Flint EP, Bosworth HB: Social support and locus of control as predictors of adherence to antidepressant medication in an elderly population.  Am J Geriatr Psychiatry 13: 157–165, 2005.
PubMed Abstract

95.   Taylor WD, Steffens DC , Payne ME, MacFall JR, Marchuk DA, Svenson IK, Krishnan KR:   Influence of serotonin transporter promoter region polymorphisms on hippocampal volumes in late-life depression.  Arch Gen Psychiatry 62: 537-544, 2005.
PubMed Abstract

94.   Taylor WD, MacFall JR, Payne ME, McQuoid DR , Steffens DC , Provenzale JM, Krishnan RR: Greater MRI lesion volumes in elderly depressed subjects than in control subjects.  Psychiatry Res 139: 1-7, 2005. 
PubMed Abstract

93.  Steffens DC, Pieper CF, Bosworth HB, MacFall JR, Provenzale JM, Payne ME, Carroll BJ, George LK, Krishnan KR: Biological and social predictors of long-term geriatric depression outcome.  Int Psychogeriatr 17: 41-56, 2005.
PubMed Abstract

92.  Steffens DC, McQuoid DR : Impact of symptoms of generalized anxiety disorder on the course of late-life depression.  Am J Geriatr Psychiatry 13: 40-47, 2005. 
PubMed Abstract

91.  Morse JQ, Robins CJ: Personality--life event congruence effects in late-life depression.  J Affect Disord 84(1): 25-31, 2005.
PubMed Abstract

90.  Kuchibhatla M, Fillenbaum GG: Modeling association in longitudinal binary outcomes: a brief review.  Aging & Mental Health 9: 196–200, 2005.
PubMed Abstract

89.  Hybels CF, Blazer DG, Steffens DC: Predictors of partial remission in older patients treated for major depression: the role of comorbid dysthymia.  Am J Geriatr Psychiatry 13(8): 713-721, 2005.
PubMed Abstract

88.  Taylor WD, MacFall JR, Payne ME, McQuoid DR , Steffens DC , Provenzale JM, Krishnan KRR: Greater MRI lesion volumes in elderly depressed subjects than in control subjects.  Psychiatry Research: Neuroimaging 139: 1-7, 2005.
PubMed Abstract

87.  Zhang X, Gainetdinov RR, Beaulieu JM, Sotnikova TD, Burch LH, Williams RB, Schwartz DA, Krishnan KRR, and Caron MG.  Report: Loss-of-Function Mutation in Tryptophan Hydroxylase-2 Identified in Unipolar Major Depression.  Neuron 45: 11-16, 2005.
PubMed Abstract

86.  Miguel-Hidalgo JJ, Dubey P, Shao Q, Stockmeier C, Rajkowska G: Unchanged packing density but altered size of neurofilament immunoreactive neurons in the prefrontal cortex in schizophrenia and major depression.  Schizophrenia Research 76: 159-171, 2005.
PubMed Abstract

Publications, 2004:

85. Robertson GS, Lee CJ, Sridhar K, Nakabeppu Y, Cheng M, Wang YM, Caron MG: Clozapine-, but not haloperidol-induced increases in deltaFosB-like immunoreactivity are completely blocked in the striatum of mice lacking D3 dopamine receptors.  Eur J Neurosci. 11: 3189-3194, 2004.

PubMed Abstract
 

84. Mohn AR, Yao W-D, Caron MG: Genetic and genomic approaches to reward and addiction.  Neuropharm 47(Suppl 1): 101-110, 2004.

PubMed Abstract
 

83. Sotnikova TD, Budygin EA, Jones SR, Dykstra LA, Caron MG, Gainetdinov RR: Dopamine transporter-dependent and independent actions of trace amine beta-phenylethylamine.  J Neurochem 91:362-373, 2004.
PubMed Abstract

82. Grove M, Demyanenko G, Echarri A, Zipfel PA, Quiroz ME, Rodriguiz RM, Playford M, Martensen SA, Robinson MR, Wetsel WC, Maness PF, Pendergast AM: Abi2 Deficient Mice Exhibit Defective Cell Migration, Aberrant Dendritic Spine Morphogenesis Deficits in Learning and Memory.  Mol Cell Biol 24: 10905-10922, 2004.
PubMed Abstract

81. Vizi ES, Zsilla G, Caron MG, Kiss JP: Uptake and release of norepinephrine by serotonergic terminals in norephinephrine transporter knock-out mice: implications for the action of selective serotonin reuptake inhibitors.  J Neurosci 24: 7888-7894, 2004.

PubMed Abstract
 

80. Keller NR, Diedrich A, Appalsamy M, Tuntrakool S, Lonce S, Finney C, Caron MG, Robertson D: Norepinephrine transporter-deficient mice exhibit excessive tachycardia and elevated blood pressure with wakefulness and activity.  Circulation 110: 191-1196, 2004.

PubMed Abstract
 

79. Gainetdinov RR, Premont RT, Bohn LM, Lefkowitz RJ, Caron MG: Desensitization of G protein-coupled receptors and neuronal functions.  Annu Rev Neurosci 27: 107-144, 2004.

PubMed Abstract
 

78. Beom S, Cheong D, Torres G, Caron MG, Kim K-M: Comparative studies of molecular mechanisms of dopamine D2 and D3 receptors for the activation of extracellular signal-regulated kinase.  J Biol Chem 279: 28304-28314, 2004.

PubMed Abstract
 

77. Beaulieu JM, Sotnikova TD, Yao W-D, Kockeritz L, Woodgett JR, Gainetdinov RR, Caron MG: Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade.  Proc Natl Acad Sci USA 101: 5099-5104, 2004.

PubMed Abstract
 

76. Yao WD, Gainetdinov RR, Arbuckle MI, Sotnikova TD, Cyr M, Beaulieu JM, Torres GE, Grant SG, Caron MG: Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity.  Neuron 41: 625-638, 2004.
PubMed Abstract

75. Gitler D, Takagishi Y, Feng J, Ren Y, Rodriguiz R, Wetsel W, Greengard P,Augustine GJ: Different roles of synapsins in excitatory and inhibitory synapses.  J Neurosci 24: 11368-11380, 2004.
PubMed Abstract

74. Quan H, Athirakul K, Wetsel WC, Torres GE, Stevens R, Chen YT, Coffman TM, Caron MG: Hypertension and impaired glycine handling in mice lacking the orphan transporter XT2.  Mol Cell Biol 24: 4166-4173, 2004.
PubMed Abstract

73. Powell SB, Lehmann-Masten VD, Paulus MP, Gainetdinov RR, Caron MG, Geyer MA: MDMA “ecstasy” alters hyperactive and perseverative behaviors in dopamine transporter knockout mice. Psychopharmacology 173: 310-317, 2004.
PubMed Abstract

72. Rodriguiz RM, Chu R, Caron MG, Wetsel WC: Aberrant responses in social interaction of dopamine transporter knockout mice.  Behav Brain Res 148: 185-198, 2004. 
PubMed Abstract

71. Barr AM, Lehmann-Masten V, Paulus M, Gainetdinov RR, Caron MG, Geyer MA: The selective serotonin-2A receptor antagonist M100907 reverses behavioral deficits in dopamine transporter knockout mice. Neuropsychopharmacology 29:221-228, 2004.
PubMed Abstract

70. Uylings HBM, Rajkowska G, Sanz Arigita E, Amunts K, Zilles K: Consequences of large interindividual variability for human brain atlases: converging macroscopical imaging and microscopical neuroanatomy.  Anat Embryology (Berl): 1-9, 2004.
PubMed Abstract

69. Stockmeier CA, Mahajan G, Konick L, Overholser JC, Jurjus G, Meltzer HY, Uylings, HBM, Friedman L, Rajkowska G: Cellular changes in the postmortem hippocampus in major depression. Biological Psychiatry 56: 640-650, 2004.
PubMed Abstract

68. Stockmeier CA, Rajkowska G: Cellular abnormalities in depression: evidence from postmortem brain tissue.  Dialogues in Clinical Neuroscience 21:109-121, 2004.
PubMed Abstract

67. Si X, Miguel-Hidalgo JJ, O’Dwyer G, Stockmeier CA , Rajkowska G: Aging dependent reductions in the level of glial Fibrillary Acidic Protein in the prefrontal cortex is lower in younger but not in older subjects with major depression. Neuropsychopharmacology 29: 2088-2096, 2004.
PubMed Abstract

66. Selemon L, Rajkowska G, Goldman-Rakic PS: Evidence for progression in prefrontal cortical pathology in late-stage Huntington’s disease.   J Comp Neurology 468: 190-204, 2004.
PubMed Abstract

65. Doty TJ, Payne ME, Steffens DC, Beyer JL, Krishnan KRR, LaBar KS: Age-dependent reductions of amygdala volume in bipolar disorder.  Journal of Cognitive Neuroscience, Supp S, 25, 2004.
PubMed Abstract

64. Lynch TR, Cheavens J, Morse JQ, Rosenthal MZ: A model predicting suicidal ideation and hopelessness in depressed older adults: The impact of emotion inhibition and affect intensity.  Aging & Mental Health 8(6): 486-497, 2004. 
PubMed Abstract

63. Fichtenholtz HM, Dean HL, Dillon DG, Yamasaki H, McCarthy G, LaBar KS : Emotion-attention network interactions during a visual oddball task.  Brain Res Cogn Brain Res 20: 67-80, 2004.
PubMed Abstract

62. Zhang X, Beaulieu JM, Sotnikova TD, Gainetdinov RR, Caron MG: Tryptophan hydroxylase-2 controls brain serotonin synthesis.  Science 305(5681): 217, 2004. 
PubMed Abstract

61. Taylor WD, McQuoid DR, Steffens DC, Krishnan KRR: Is there a Definition of Remission in Late-Life Depression that Predicts Later Relapse?  Neuropsychopharmacology 229(12): 2272-2277, 2004. 
PubMed Abstract

60.  Taylor WD, McQuoid DR , Krishnan KRR: Medical comorbidity in late-life depression.  Int J Geriatr Psychiatry 19(10): 935, 2004.
PubMed Abstract

59.  Taylor WD, MacFall JR, Payne ME, McQuoid DR, Provenzale JM, Steffens DC, Krishnan KRR: Late-life depression and abnormalities in dorsolateral prefrontal cortex white matter microstructure.  Am J Psychiatry 161: 1293-1296, 2004. 
PubMed Abstract

58.  Taylor WD, Hsu E, Krishnan KRR, MacFall JR: Diffusion tensor imaging: background, potential, and utility in psychiatric research.  Biological Psychiatry 55: 201-207, 2004. 
PubMed Abstract

57.  Steffens DC, Welsh-Bohmer KA, Burke JR, Plassman BL, Beyer JL, Gersing KR, Potter GG: Methodology and preliminary results from the neurocognitive outcomes of depression in the elderly study.  J Geriatr Psychiatry Neurol 17(4): 202-211, 2004.
PubMed Abstract

56.  Steffens DC: Establishing diagnostic criteria for vascular depression. J Neurol Sci 226(1-2): 59-62, 2004.
PubMed Abstract

55.  Potter GG, Kittinger JD, Wagner HR, Steffens DC, Krishnan KRR: Prefrontal neuropsychological predictors of treatment remission in late-life depression. Neuropsychopharmacology 29(12): 2266-2271, 2004. 
PubMed Abstract

54.  Morse JQ, Lynch TR: A preliminary investigation of self-reported personality disorders in late life: prevalence, predictors of depressive severity, and clinical correlates.  Aging Ment Health 8(4): 307-15, 2004.
PubMed Abstract

53.  Doraiswamy PR, Steffens DC , McQouid DR : Statin use and hippocampal volumes in elderly subjects at risk for Alzheimer's disease: a pilot observational study.  Am J Alz Disease Other Dementias 19: 275-278, 2004.
PubMed Abstract

52.  Krishnan KRR, Taylor WD, McQuoid DR, MacFall JR, Payne ME, Provenzale JM, Steffens DC: Clinical characteristics of MRI-defined subcortical ischemic depression.  Biological Psychiatry 55(4): 390-397, 2004.  
PubMed Abstract

Publications, 2003:

51. Trinh JV, Nehrenberg DL, Jacobsen JP, Caron MG, Wetsel WC: Differential psychostimulant-induced activation of neural circuits in dopamine transporter knockout and wild type mice.  Neurosci 118: 297-310, 2003.

50. Miyakawa T, Leiter LM, Gerber DJ, Gainetdinov RR, Sotnikova TD, Zeng H, Caron MG, Tonegawa S: Conditional calcineurin knockout mice exhibit multiple abnormal behaviors related to schizophrenia.  Proc Natl Acad Sci USA 100: 8987-8992, 2003.

49. Torres GE, Caron MG: Center stage for the serotonin transporter: A gain-of-function polymorphism in persons with obsessive-compulsive disorder.  Mol Pharmacol 64: 196-198, 2003.

48. Torres GE, Gainetdinov RR, Caron MG: Plasma membrane monoamine transporters: structure, regulation and function.  Nature Rev Neurosci 4: 13-25, 2003.

47. Torres GE, Carneiro A, Fiorentini C, Sweeney A, Seamans K, Yao WD, Caron MG:  Oligomerization and trafficking of the human dopamine transporter: Mutational analysis identifies critical domains involved in the functional expression of the transporter.  J Biol Chem 278: 2731-2739, 2003.

46. Gainetdinov RR, Caron MG: Monoamine transporters: from genes to behavior.  Ann Rev Pharmacol Toxicol 43: 261-284, 2003.

45. Stockmeier CA: Involvement of serotonin in depression: evidence from postmortem and imaging studies of serotonin receptors and the transporter.  J Psychiatric Res 37: 357-373, 2003.

44. Selemon L, Rajkowska G: Cellular pathology in the dorsolateral prefrontal cortex distinguishes schizophrenia from bipolar disorder.  Current Molecular Medicine 3: 427-436, 2003.

43. Rajkowska, G: Depression: What we can learn from postmortem studies.  Neuroscientist 9(4): 273-284, 2003.

42. Lynch TR, Morse JQ, Mendelson T, Robins CJ: Dialectical behavior therapy for depressed older adults: A randomized pilot study.  American Journal of Geriatric Psychiatry 11(1): 33-45, 2003.

41. Sha L, Guo H, Song AW: An improved non-uniform fast fourier transform for spiral MRI imaging.  Journal of Magnetic Resonance 162: 250-258, 2003.

40. Williams RB, Marchuck DA, Gadde KM, et al: Serotonin-related gene polymorphisms and central nervous system serotonin function.  Neuropsychopharmacol 28: 533-541, 2003.

39. Taylor WD, MacFall JR, Provenzale JM, Payne ME, McQuoid DR, Steffens DC, Krishnan KR: Serial MR imaging of hyperintense white matter lesion volumes in elderly patients: correlation with vascular risk factors.  American Journal of Roentgenology 181: 571-576, 2003.

38. Taylor WD, MacFall JR, Steffens DC, Payne ME, Provenzale JM, KrishnanKR: Localization of age-associated white matter hyperintensities inlate-life depression.  Prog  Neuropsychopharmacol Biol Psychiatry 27(3): 539-544, 2003.

37. Taylor WD, Steffens DC , McQuoid DR , Payne ME, Lee SH, Lai TJ, Krishnan KR: Smaller orbital frontal cortex volumes associated with functional disability in depressed elders.  Biol Psychiatry 53(2): 144-149, 2003.

36. Steffens DC, Trost WT, Payne ME, Hybels CF, MacFall JR: Apolipoprotein E genotype and subcortical vascular lesions in older depressed patients and control subjects. Biol Psychiatry 54(7): 674-681, 2003.

35. Steffens DC, Taylor WD, Krishnan: Progression of subcortical ischemic disease from vascular depression to vascular dementia.  Am J Psychiatry 160(10): 1751-1756, 2003.

34. Steffens DC, McQuoid DR, Krishnan KR: Partial response as a predictor of outcome in geriatric depression.  Am J Geriatr Psychiatry 11(3): 340-348, 2003.

33. Parker RD , Flint EP, Bosworth HB, Pieper CF, Steffens DC: A three-factor analytic model of the MADRS in geriatric depression.  Int J Geriatr Psychiatry 18(1): 73-77, 2003.

32. Levy RM, Steffens DC , McQuoid DR , Provenzale JM, MacFall JR, Krishnan KRR: MRI lesion severity and mortality in geriatric depression.  Am J Geriatr Psychiatry 11(6): 678-682, 2003.

31. Lee S-H, Payne ME, Steffens DC, McQuoid DR, Lai T-J, Provenzale JM, Krishnan KRR:   Subcortical lesion severity and orbitofrontal cortex volume in geriatric depression.  Biol Psychiatry 54(5): 529-533, 2003.

30.  Krishnan KR: Comorbidity and depression treatment.  Biol Psychiatry 53(8): 701-706, 2003.

29.  Hulette CM: Brain banking in the United States .  J Neuropathol Exp Neurol 62(7): 715-722, 2003.

28.  Brummett BH, Siegler IC, McQuoid DR , Svenson IK, Marchuk DA, Steffens DC : Associations among the NEO Personality Inventory, Revised and the serotonin transporter gene-linked polymorphic region in elders: effects of depression and gender.  Psychiatr Genet 3(1): 3-18, 2003.

27.  Bosworth HB, Bartash RM, Olsen MK, Steffens DC : The association of psychosocial factors and depression with hypertension among older adults.  Int J Geriatr Psychiatry 18(12): 1142-1148, 2003.

26.  Bosworth HB, Park KS , McQuoid DR , Hays JC, Steffens DC : The impact of religious practice and religious coping on geriatric depression.  Int J Geriatr Psychiatry 18(10): 905-14, 2003.

25.  Taylor WD, Steffens DC, MacFall JR, McQuoid DR, Payne ME, Provenzale JM, Krishnan KRR: White matter hyperintensity progression and late-life depression outcomes.  Archives of General Psychiatry 60: 1090-1096, 2003.

24.  Steffens DC, Taylor WD, Krishnan KRR: Progression of subcortical ischemic disease from vascular depression to vascular dementia.  American Journal of Psychiatry 160: 1751-1756, 2003.

23.  Miguel-Hidalgo JJ, Rajkowska G: Comparison of prefrontal cell pathology between depression and alcohol dependence.  J Psychiatric Research 37: 411-420, 2003.

22.  Rajkowska G, Miguel-Hidalgo JJ, Jiang J, Nizigiye J, Overholser JC, Meltzer HY, Jurjus G, Stockmeier CA , Krishnan RR:  Depression in elderly is associated with blood vessels pathology in lateral orbitofrontal cortex. Biol Psych 53: 32S, 2003.

Publications, 2002:

              21. Joseph JD, Wang YM, Miles PR, Budygin EA, Picetti R, Gainetdinov RR, Caron MG, Wightman RM: Dopamine autoreceptor regulation of release and uptake in mouse brain slices in the absence of D(3) receptors.  Neurosci 112: 39-49, 2002.

20. Haller J, Bakos N, Rodriguiz RM, Caron MG, Wetsel WC, Liposits Z: Behavioral responses to social stress in noradrenaline transporter knockout mice: effects on social behavior and depression.  Brain Res Bull. 58:279-284, 2002.

19. Gainetdinov RR, Sotnikova TD, Caron MG: Monoamine transporter pharmacology and mutant mice.  Trends Pharmacol Sci 23: 367-373, 2002.

18. Hall FS, Li XF, Sora I, Xu F, Caron MG, Lesch KP, Murphy DL, Uhl GR: Cocaine mechanisms: enhanced cocaine, fluoxetine and nisoxetine place preferences following monoamine transporter deletions.  Neurosci 1: 153-161, 2002.

17. Carneiro AM, Ingram SL, Beaulieu JM, Sweeney A, Amara SG, Thomas SM, Caron MG,Torres GE: The multiple LIM domain-containing adaptor protein Hic-5 synaptically co-localizes and interacts with the dopamaine transporter.  J Neurosci 22: 7045-7054, 2002.

16. Barbosa J Jr., Ferreira LT, Martins-Silva C, Santos MS , Torres GE, Caron MG, Gomez MV, Ferguson SS, Prado MA, Prado VF: Trafficking of the vesicular acetylcholine transporter in SN56 cells: a dynamin-sensitive step and interaction with the AP-2 adaptor complex.  J Neurochem 82: 1221-1228, 2002.

15. Stockmeier CA, Shi X, Konick L, Overholser JC, Jurjus G, Meltzer HY, Friedman L, Blier P, and Rajkowska G: Neurokinin-1 receptors are decreased in major depressive disorder.  Neuroreport 13: 1223-1227, 2002.

14. Selemon LD, Goldman-Rakic PS, Rajkowska G: Two-Dimension versus Three-29: 2088-2096Dimension cell counting. Biological Psychiatry 51: 837-939, 2002.

13. Rajkowska G: Cell Pathology in mood disorders.  Seminars in Clinical Neuropsychiatry 7: 1-12, 2002.

12. Miguel-Hidalgo JJ, Rajkowska G: Morphological brain changes in depression: can antidepressants reverse them. Journal of CNS Drugs 16: 361-372, 2002.

11.  Lynch TR, Morse JQ, Vitt CM: Dialectical behavior therapy for depressed older adults.  Behavior Therapist 25(1): 7-8, 2002.

10.  Taylor WD, Krishnan KR.  Management of late-life depression: focus on comorbid conditions.  Psychopharmacol Bull 36(4, Suppl 3): 113-130, 2002.

9. Payne ME, Fetzer DL, McFall JR, Provenzale JM, Byrum CE, Krishnan KR: Development of a semi-automated method for quantification of MRI gray and white matter lesions in geriatric subjects.  Psychiatry Research 115(1-2): 63-77, 2002.

8. Salloway S, Boyle PA, Correia S, Malloy PF, Cahn-Weiner DA, Schneider L, Krishnan KR, Nakra R: The relationship of MRI subcortical hyperintensities to treatment response in a trial of sertraline in geriatric depressed outpatients.  American J Geriatric Psychiatry 10(1): 107-111, 2002.

7.  Beyer JL, Krishnan KR: Volumetric brain imaging findings in mood disorders.  Bipolar Disorder 4(2): 89-104, 2002.

6. Kim DM, Xanthakos SA, Tupler LA, Barboriak DP, Charles HC, MacFall JR, Krishnan KR: MR signal intensity of gray matter/white matter contrast and intracranial fat: effects of age and sex.  Psychiatry Research 114(3): 149-161, 2002.

5. Salloway S, Correia S, Boyle P, Malloy P, Schneider L, Lavretsky H, Sackheim H, Roose S, Krishnan KR: MRI subcortical hyperintensities in old and very old depressed outpatients: the important role of age in late-life depression.  J Neurol Science 203-204: 227-233, 2002.

4. Steffens DC, Krishnan KR, Crump C, Burke GL: Cerebrovascular disease and evolution of depressive symptoms in the cardiovascular health study.  Stroke 33(6): 1636-1644, 2002.

3. Tupler LA, Krishnan KR, McDonald WM, Dombeck CB, D’Souza S, Steffens DC : Anatomic location and laterality of MRI signal hyperintensities in late-life depression.  Journal of Psychosomatic Medicine Research 53(2): 665-676, 2002.

Publications, 2001:

2.  Steffens DC, Wagner HR, Levy RM, Horn KA, Krishnan KR: Performance feedback deficit in geriatric depression. Biol Psychiatry 50(5): 358-363, 2001.

1.  Williams RB, Marchuck DA, Gadde KM, et al: Central nervous system serotonin function and cardiovascular responses to stress.  Psychosomatic Med 63: 300-305, 2001.